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Likarda featured on SelectScience.net

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Automating Assay Development for Early Stage Drug Discovery

Likarda works with clients at the early stages of drug development and discovery.  Dr Lisa Stehno-Bittel, President & Co-founder of Likarda, discusses how the company develops 3D cell clusters, which are indicative of native tissues in the body, for use in cell-based assays. Hear from research scientist Stephen Harrington PhD, Likarda’s Director of Production, how the team has utilized automation to increase throughput and reproducibility, most recently employing the Integra Assist to bridge the gap between manual bench work and complete automation. Read More

Understanding CRO 3.0

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Understanding the past, present and future roles of CROs in early phase drug discovery

As the race is constant to bring new drugs to market, pharmaceutical and nutraceutical companies and science entrepreneurs turn to contract research organizations (CROs) to provide or supplement research processes. This puts an emphasis on providing pharma and entrepreneurs with custom assays, tools and information that improve their workflow efficiency and speed to market. This article examines how CROs influence the research environment and how they can alter their roles to support pharma and science entrepreneurs in intense market competition, reducing the exorbitant time and cost associated with early phase drug discovery. It explores the roles of CROs’ progression in helping pharma and entrepreneurs move confidently forward from the early discovery phase in the past, now and in the future. Read More

Buzz for BIO: Moving Early-Phase Discovery Forward with Confidence

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Custom 3D Assays and Research Services Result in Better Predictability of Drug Treatment Response

Using our proprietary 3D screening approach, Likarda researchers test different drugs with known effects in humans using the conventional pharmaceutical approach and our 3D cell cluster. In each case, the results of our 3D assays better mimicked how the drugs work in humans. Compared to conventional methods, our process allows you to better predict responses to drug treatments. And as a CRO, our turnaround time and costs are more efficient. Read More

Lindsey Ott Delivers Well Received Poster Session on Likarda’s New 3d Liver Spheroid System at 2016 AAPS Annual Meeting

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Likarda’s product innovation scientist, Lindsey Ott, Ph.D., was a presenting author for a poster session at the 2016 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition on November 16 in Denver, CO. Session attendees learned about a promising three-dimensional cell-based method to evaluate liver metabolism and toxicity for early stage drug discovery via Likarda’s 3D liver spheroid system. Read More

Testing Drug Toxicity and Curing Disease Using Three-Dimensional Cell Clusters

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For decades, tests to understand how the body works, and how it responds to drugs have been conducted with a single layer of cells attached to a plastic petri dish. In other words, the testing system critical to discovering cures operates in a 2D environment. Therein lies the problem. We live in a 3D world, and our bodies are made up of cells attached to each other in a moving 3D structure. 2D testing isn’t a true predictor of how cells react to drugs, but it’s used because it has been the available option. Read More