One of the best ways to keep up with Likarda and follow us in the national and local news is by browsing our recent news articles and media mentions.

Likarda’s Proprietary 3D Cluster Technology, the CC Microplate™, is Now Available for Purchase

By | News & Media, Uncategorized

CC Microplate from LikardaA chemical’s toxicity to humans is one of the leading causes for promising, new drugs to fail. Often, a drug can show positive results in improving one condition, yet have toxic effects on other human organs. Until recently, researchers’ ability to test how human and animal cells respond to a drug was limited to the confines of a two-dimensional petri dish.

Though widely used, 2D testing is far from ideal because this method cannot accurately predict cells’ reaction given that, in the body, cells attach to one another and move three dimensionally. In addition, valuable time and expense are wasted testing a new drug in two dimensions only to have it fail; those same resources could be allocated sooner to the next promising option. After all, curing diseases such as diabetes and cancer is a race against time.

The limitations of two-dimensional testing were overcome when researchers discovered a way to create and study small 3D structures, miniaturized organ-like cell clusters. Yet this too was not without challenges since 3D cells are hard to work with and very complicated.

Likarda Invented the CC Microplate to Enhance Miniature 3D Cell Structure Formation
Likarda dramatically advanced 3D cluster technology by inventing its CC Microplate, allowing life-saving treatments to go to market faster and more affordably. These patented CC Microplates can produce and test 200,000 clusters of cells in the same amount of space that traditional microplates form and test 384 cell clusters, which saves significant time and money. Cell clusters formed in the CC Microplate can be used for:

  • Drug testing
  • Developing cell-based transplantations
  • Regenerative medicine

The CC Microplate can be used with screening methods ranging from biochemical assays to phenotypic or high content screening.

The CC Microplate Improves Prediction of the Body’s Response to a Drug
The CC Microplate gives you the ability to form cell clusters from different tissues and populations, including those specific to age, sex, species, and breed. Cell clusters formed in the CC Microplate have a low diffusion barrier and are in close proximity so they can attach and react naturally to each other, as well as the drug with which they’re being tested. This results in better prediction of the body’s response. For ease of use, cell clusters can even be made from cryopreserved cells.

The  CC Microplate is Vastly More Efficient Than Other Microplates
Using this proprietary cell culture system can give you an advantage over your competitors by offering a truly scalable solution with vast applicability. Cell clusters, both animal and human, developed in the microplate are uniform in size and can be maintained for longer time periods. Likarda’s CC Microplate is currently available in a 384-well plate format.  This SLAS-compliant format can be readily integrated into the lab and works with existing automated equipment and methodologies.

Being the first to market with your drug discovery is critical to improving health outcomes for humans and animals and establishing market share. Move forward confidently by using Likarda’s CC Microplate in your 3D cell research.

Contact us for more information on purchasing the CC Microplate.

$4 Million Animal Health Investment Means More Strides for Treating Diabetic Pets

By | News & Media

Werth Family Investment Associates backs Likarda’s proprietary Kanslet™ diabetes treatment in dogs and cats.


KANSAS CITY, Kan. – Cutting-edge biotech research laboratory, Likarda, has received $4,000,000 in Series A funding from Werth Family Investment Associates, bringing the promise of future diabetes treatment options to dogs and cats.

Likarda is the leading regenerative medicine company for companion animals. They have discovered—and are commercializing—a better way to manage diabetes in dogs and cats. Their insulin-producing cell clusters, called the Kanslet™, can be infused into animals with diabetes. The process allows veterinarians to offer a minimally invasive, cost-effective answer to pet owners battling the burden of diabetes in dogs and cats.

Read More

Likarda Outgrows Space at KU Incubator

By | News & Media

Biotech research lab continues promising growth with move.


KANSAS CITY, Kan. – Cutting-edge biotech research laboratory Likarda has outgrown its space at the Bioscience & Technology Business Center (BTBC) on the KU Medical Center Campus and will move near the former Marion Laboratories campus in south Kansas City, Missouri, in October 2017. The move more than doubles the square footage of their former laboratory space, allowing Likarda to continue to scale up operations.

Likarda has occupied lab space at the BTBC since they were founded in May 2012. Since that time, their success as a pharmaceutical contract research organization and pioneer in animal health has seen the lab space grow to encompass the ground floor of the BTBC. As the race is constant to bring new drugs to market, pharmaceutical and nutraceutical companies and science entrepreneurs turn to contract research organizations (CROs) like Likarda to provide or supplement the research process.

Read More

Likarda featured on

By | News & Media

Automating Assay Development for Early Stage Drug Discovery

Likarda works with clients at the early stages of drug development and discovery.  Dr Lisa Stehno-Bittel, President & Co-founder of Likarda, discusses how the company develops 3D cell clusters, which are indicative of native tissues in the body, for use in cell-based assays. Hear from research scientist Stephen Harrington PhD, Likarda’s Director of Production, how the team has utilized automation to increase throughput and reproducibility, most recently employing the Integra Assist to bridge the gap between manual bench work and complete automation. Read More

Understanding CRO 3.0

By | News & Media, Uncategorized | No Comments

Understanding the past, present and future roles of CROs in early phase drug discovery

As the race is constant to bring new drugs to market, pharmaceutical and nutraceutical companies and science entrepreneurs turn to contract research organizations (CROs) to provide or supplement research processes. This puts an emphasis on providing pharma and entrepreneurs with custom assays, tools and information that improve their workflow efficiency and speed to market. This article examines how CROs influence the research environment and how they can alter their roles to support pharma and science entrepreneurs in intense market competition, reducing the exorbitant time and cost associated with early phase drug discovery. It explores the roles of CROs’ progression in helping pharma and entrepreneurs move confidently forward from the early discovery phase in the past, now and in the future. Read More

Moving Early-Phase Discovery Forward with Confidence

By | News & Media | No Comments

Custom 3D Assays and Research Services Result in Better Predictability of Drug Treatment Response

Using our proprietary 3D screening approach, Likarda researchers test different drugs with known effects in humans using the conventional pharmaceutical approach and our 3D cell cluster. In each case, the results of our 3D assays better mimicked how the drugs work in humans. Compared to conventional methods, our process allows you to better predict responses to drug treatments. And as a CRO, our turnaround time and costs are more efficient. Read More

Lindsey Ott Delivers Well Received Poster Session on Likarda’s New 3d Liver Spheroid System at 2016 AAPS Annual Meeting

By | News & Media | No Comments

Likarda’s product innovation scientist, Lindsey Ott, Ph.D., was a presenting author for a poster session at the 2016 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition on November 16 in Denver, CO. Session attendees learned about a promising three-dimensional cell-based method to evaluate liver metabolism and toxicity for early stage drug discovery via Likarda’s 3D liver spheroid system. Read More

Testing Drug Toxicity and Curing Disease Using Three-Dimensional Cell Clusters

By | News & Media | No Comments

For decades, tests to understand how the body works, and how it responds to drugs have been conducted with a single layer of cells attached to a plastic petri dish. In other words, the testing system critical to discovering cures operates in a 2D environment. Therein lies the problem. We live in a 3D world, and our bodies are made up of cells attached to each other in a moving 3D structure. 2D testing isn’t a true predictor of how cells react to drugs, but it’s used because it has been the available option. Read More