Proof to Move Forward with Confidence

Confidently navigate a complex market with our multifaceted early-phase research tools and processes. Using our proprietary 3D screening approach, we have tested different drugs with known effects in humans using the conventional pharmaceutical approach and our 3D cell cluster. In each case, the results of our 3D approach better mimicked how the drugs work in humans. Compared to conventional methods, our process allows you to better predict responses to drug treatments. Yet the market has been slow to develop efficient methods of testing in 3D.

Likarda has developed and worked with 3D models in cancer, diabetes, stem cells, liver, and a number of other areas.  We review all projects that walk in the door and can develop cell-based assays tailored to a specific cell type of interest, whether it is human, animal, cell lines or other source of origin.

While competitors can create and test 384 cell clusters in a normal cell culture plate, our micromold allows the formation and testing of 200,000 clusters in the same space. Our approach to 3D cell-based testing is highly efficient, allowing us to return findings to clients with speed and accuracy.

We achieve accurate, high-quality results across all phases of drug discovery and development, including:

  • Toxicology
  • Metabolism
  • Cell health assays
  • Pharmacodynamics studies
  • Other cell-based assays
  • Preclinical animal studies
  • Mass spectrometry
  • Analytical chemistry

Analytical services are composed of comprehensive, state-of-the-art assay development, transfer, validation, and sample analysis.

Plus, we have a full suite of stability services, including environmental and photostability storage and testing that meet ICH guidelines. All of our systems are constantly monitored to ensure performance and security and involve the following factors:

  • Cold storage (-80°C, -20°C, +4°C)
  • Room temperature
  • Environmental stability (controlled temp and RH)
  • Freeze/thaw
  • Photostability
  • Other stability conditions available upon request

Likarda also offers additional support services:

  • Review and interpretation of all study-related data
  • IND-enabling recommendations and studies
  • Preparation of peer-reviewed and expert opinion publications
  • Review of materials for brochures or collateral materials
  • Assistance or presentation of oral presentations for business or science audiences
  • Expedited services available (rapid turnaround times)
  • Likarda can offer GxP-compliant services