Core-Shell Spherificationâ„¢: an immunoprotective shield for all types of cell-based treatments
When donor cells are transplanted into a recipient’s body without protection, the immune system attacks them as foreign. Traditionally, systemic immunosuppressive drugs are administered in order to prevent the attack and protect the cell transplant.
Instead, we microencapsulate (coat) our cells and cell clusters in a hydrogel material that blocks the immune system from attacking. Core-Shell Spherificationâ„¢(CSS) is our patented process that microencapsulates cells and cell clusters using hydrogels that were once thought to be usable only in a bulk or large format.