EnduraCell™Immunoprotective Cell Encapsulation for Long-Term Delivery of therapeutic cells and proteins without systemic immunosuppression
EnduraCell™ is a durable, biocompatible hydrogel encapsulation platform engineered to provide immune shielding and sustained function for cell-based therapies. Designed for applications where cellular integration is not required, EnduraCell™ maintains the viability and therapeutic output of encapsulated cells over extended durations—without the need for systemic immunosuppression or surgical retrieval.
Primary Benefits of EnduraCell™
Ideal for cell therapies where the output, not the integration, is the goal.
Protects cells that produce proteins or enzymes for therapeutic use.
No retrieval or systemic immunosuppression required.
Maintains continuous, localized release of therapeutic agents
Real-World Applications
Built for long-term delivery of therapeutic proteins and enzymes, EnduraCell™ enables durable, immune-protected treatments that don’t require surgical retrieval, making it ideal for chronic conditions managed through sustained cellular output.
Diabetes Therapy
Used to encapsulate insulin-producing cells in a diabetic dog, eliminating daily injections with no immune rejection.
Liver Disease
Human hepatocyte spheroids encapsulated in EnduraCell™ sustained albumin secretion and CYP activity in vivo for 30+ days, outperforming alginate and unencapsulated controls.
Hormone & Enzyme Replacement
By protecting cells from immune attack while allowing the diffusion of oxygen, nutrients, and therapeutic proteins, EnduraCell™ enables safer, longer-lasting cell therapies for chronic conditions.
“This landmark study with EnduraCell™ showed that durable, safe, and effective cell therapy for diabetes is possible, laying the foundation for Likarda’s Core-Shell Spherification® platform.”
Explore Other Cell Therapies
Discover complementary platforms designed for sustained delivery, immune protection, and therapeutic precision.
Let’s Collaborate
Considering EnduraCell™ for long-term protein or hormone delivery? Explore its immune shielding, sustained release, and proven in vivo performance.