Introduction In the recent past, the field of regenerative medicine has gained increasing prominence as a new category of therapies with the ability to cure chronic diseases. Continued innovations in deriving new sources and classifications of stem cells have...

Cell therapies are heralding a transformative age in medicine, offering promising new avenues for treating a variety of debilitating diseases. As we shift our focus from merely alleviating symptoms to discovering potential cures, we enter a realm of unprecedented...

Macrodevices for Cell Therapies When discussing cell therapies, the term macroencapsulation indicates a device that is larger than 1 mm in dimensions that is designed to protect cells from an immune system attack. In Part I of this series, we reviewed the advantages...

On average, there are over 2600 clinical trials for cell and gene therapy products on any given day. Yet very few of these products have made it to market to have an impact on society. For example, the largest number of newly approved cell or gene therapies were in...

Cell and gene therapies are no longer a promise for the future. They are here today.  In fields like oncology, pediatrics, and hematology, gene and cell therapies are revolutionizing care for chronic and terminal diseases.  However, with the exception of patients...

Hydrogels start out as liquid solutions of individual polymer chains dissolved in an aqueous (water-based) solvent. To transform this liquid solution into a solid hydrogel, the polymer chains have to be connected together through a process called crosslinking, also...

As medical innovations advance, cells can be used to repair sites of injury or reverse the effects of disease. However, one of the major challenges for the cell therapy field is the lack of a defined delivery system. Although a delivery system can solve numerous...